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DNA transposition is nature's way of cutting and pasting genetic information.

At Domus Biotechnologies, we have harnessed this power.

Learn more

DNA transposition is nature's way of cutting and pasting genetic information.

At Domus Biotechnologies, we have harnessed this power.

Learn more
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Mu transposase

Our Mu transposase is the wild type enzyme from the Mu phage. The natural function of the enzyme is to amplify the phage genome in the infected bacterial cells by transposing the phage genome repeatedly.

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Hyperactive Mu transposase

Our hyperactive Mu transposase is an engineered version of the wild type transposase enzyme.

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Haloferax volcanii insertion library

Our Haloferax volcanii library contains an exhaustive pool of mutants, in which each clone contains one genomic insertion of a transposon in a random position and with a full-genome coverage.  

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We provide cutting-edge tools for DNA transposition - from the molecular machinery to sophisticated applications.

Mu transposase

Our Mu transposase is the wild type enzyme from the Mu phage. The natural function of the enzyme is to amplify the phage genome in the infected bacterial cells by transposing the phage genome repeatedly. We have isolated the enzyme responsible for this transposition and provide it here purified.

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Hyperactive Mu transposase

Our hyperactive Mu transposase is an engineered version of the wild type transposase enzyme. Through protein engineering we have increased the transposition capacity of the wild-type Mua 10-fold.

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Haloferax volcanii
insertion library

Transposons are powerful tools for the generation of insertion mutant libraries in various organisms, in which each gene is tagged by an insertion. Our Haloferax volcanii library contains an exhaustive pool of mutants, in which each clone contains one genomic insertion of a transposon in a random position and with a full-genome coverage.

Shop nowRead more